Jesper

Meet Jesper. He’s a Senior Director in Machine Intelligence.

A tale of simulation and automation

My job is about applying advanced techniques within biophysics and machine learning to rationalise complex data – and the ultimate aim of that is to help design new molecules for patients. That is, essentially, what I do as the head of the Machine Intelligence department in the Digital Science and Innovation area in R&ED. Our team is responsible for advanced AI, machine learning, and statistics to support the scientists within computational drug discovery, computational biology, human genetics, and computational precision health.

But you got it back, right?

I've forgotten my bike on the train... three times.

Joining

The bigger picture

I chose to seek job opportunities at Novo Nordisk because it had a very good reputation, both ethically and workwise. And because I saw an opportunity to contribute to make a real and meaningful difference for patients by applying my scientific background in theoretical physics and machine learning in a larger cross-disciplinary context.

Collaboration

Overcoming challenges

When I joined Novo Nordisk, I was surprised by the high scientific level on one hand, but also by the legacy of working processes and fragmented IT solutions on the other. Combined, these aspects create hindrances to the implementation of modern and high-throughput data acquisition and analyses. However, this is something we're ambitiously trying to change.

The pharmaceutical industry is undergoing a transformative process where digital solutions are pivotal. The discovery of novel drugs for challenging diseases will rely on modern high-throughput assays and advanced analysis methodologies, and this can only be realised by engaging with experts in the digital and technical domains. I believe we're succeeding in this at Novo Nordisk by pooling the skills and efforts of chemists, bioinformaticians, data scientists, engineers, and software engineers.

We want to give the scientists here in Novo Nordisk better tools to decipher the hidden patterns in our data, and that's what I feel my work is all about
Jesper Ferkinghoff Borg, Senior Director in Machine Intelligence at Novo Nordisk

Automatic for the people

I founded the 'BayesChrom' project for automated analysis of chromatography, which is the most widely used experimental technique at Novo Nordisk for separating and quantifying molecular mixtures. Each year, Novo Nordisk produces more than 1.5 million chromatograms (i.e., the electronic file or hardcopy containing the information generated from the chromatography process), and until recently, we had lab techs and chemists manually conducting analyses. With the new digital solution, this process will be fully automated with much greater precision and speed.

Communities

Engaging discussions

Internally and externally, I’m affiliated with communities themed around Machine Learning, and more specifically within physics, chemistry, and biology. But I am also part of Novo Nordisk’s communities for IT-solutions, data management, and scientific engineering.

Where it all began

❶❷ At the age of twelve, I wrote down all the combinations for a typical 6-pin bicycle lock, and subsequently, I helped kids in the neighbourhood with opening bicycles belonging to 'aunts' and 'uncles' who had forgotten their code. This went on until... well...

Tech stack
docker
python
Azure
r
github
AWS

We're seeing a theme here

∞ My wife keeps a collection of images of strange places where I have left my glasses.

My Career

Hold your breath

➔ Obtaining a PhD degree in theoretical biophysics from Niels Bohr Institute (2001).
➔ Co-creator of a world-known and widely used algorithm (Fold-X) in biochemistry for protein energy calculations (2005).
➔ Appointed Associate Professor, dept. Biomedical Engineering, DTU-Electro (2007-), and establishing a research group within biophysics and machine learning.
➔ Senior analyst in Quantitative Research, Danske Market (2011).

And then...

➔ Co-editor of the book “Bayesian Methods in Structural Biology” (Springer-Verlag, 2012)
➔ Associate Professor / Senior Researcher in cellular signalling group, Systems Biology, DTU (2013-)
➔ Principal Scientist, “Advanced Analytics”, Global Research Technologies, R&ED, Novo Nordisk (2016-2019)

... a few more things.

➔ Inventor and Product Owner of “BayesChrom” project in Novo Nordisk (2019-present)
➔ Research Director, Global Research Tech. R&ED, Novo Nordisk (2021-2023)
➔ Senior Director, Head of “Machine Intelligence” department, Digital Science and Innovation, R&ED, Novo-Nordisk (2023-)

Now... Nuclear

➔ To simulate nuclear dynamics during my M.Sc., I became proficient with C programming
➔ As part of the development of protein dynamics simulations during my Ph.D. and PostDoc, I learned how to use object-oriented programming, such as C++ and GitLab.
➔ In 2013, I joined a systems biology group and learned how to use R, as it was the preferred language for bioinformaticians at the time

... and breathe.

➔ For statistical analysis in systems biology, I learned how to use Python and the associated libraries to apply it in more advanced machine learning.
➔ For my work at Novo Nordisk, especially with regards to cloud computing, I’ve learned to use Docker container technologies.

Just a few – but quite – important personal highlights

␥ As a child, learning to play the piano from my grandmother
␥ My high school years, during which I formed most of my closest friendships
␥ Enrolling to study Physics at the University of Copenhagen in 1992
␥ Meeting and marrying Lotta in 2001. Still happily married
␥ Father of two children, Daniel (2003) and Rebecca (2006)

Want to work with Jesper? Then join us…